Magnesium L-Threonate: Everything you Need to Know
You might already know that magnesium is important — it supports muscles, nerves, sleep, and even stress. But not all magnesium is the same. There’s a particular form that’s been making waves in the health world: Magnesium L-Threonate.
So what makes this form of magnesium so special? And why are so many of our customers asking about it? Let's break it down.
What is Magnesium L-Threonate?
Magnesium L-Threonate (often shortened to Magtein®, its patented form) is a newer, more bioavailable form of magnesium. Unlike other magnesium supplements, Magnesium L-Threonate is specially formulated to cross the blood-brain barrier, allowing it to directly elevate magnesium levels in the brain.
Why does that matter? Because higher brain magnesium levels = better cognitive performance.
In fact, in a groundbreaking animal study published in Neuron, researchers found that increasing brain magnesium via Magnesium L-Threonate improved learning abilities, working memory, and short- and long-term memory in rats — and these benefits extended even to aging subjects.
What Makes it Different from Other Magnesium Supplements?
Most magnesium supplements, like magnesium oxide or citrate, are great for muscle support or digestion. Magnesium glycinate is another popular form, especially for calming the nervous system and supporting better sleep, thanks to its gentle, well-absorbed nature.
But they don’t do much for your brain. That’s because they have limited ability to increase brain magnesium levels.
Magnesium L-Threonate, however:
- Penetrates the brain better than other forms
- Boosts synaptic density (aka, it helps brain cells communicate better)
- Has neuroprotective benefits that can support long-term brain health
Think of it as your go-to magnesium for mental clarity, focus, and memory.
Backed by Research: What the Science Says
🧠 Memory and Learning
A 2010 study in Neuron showed that Magnesium L-Threonate enhanced both short-term and long-term memory in rats by 60% and 100%, respectively. These are impressive numbers, especially when you consider how notoriously difficult it is to boost memory through supplementation alone.
In humans, a 2016 randomized controlled trial published in The Journal of Alzheimer’s Disease reported that daily supplementation of Magnesium L-Threonate improved cognitive abilities in adults aged 50–70 who were experiencing mild cognitive impairment. Participants showed improvement in executive function, working memory, and attention — all without serious side effects.
🧘 Stress and Anxiety Support
Magnesium is often called "nature’s chill pill" — and for good reason. It regulates neurotransmitters like GABA, which helps the brain stay calm and collected. But it’s not just any magnesium that helps.
In one double-blind study, Magnesium L-Threonate supplementation significantly reduced anxiety-like behavior and improved stress resilience in test subjects [3]. Though more human studies are needed, these early results are promising.
Who Can Benefit from Magnesium L-Threonate?
This isn't just for people concerned about cognitive decline — Magnesium L-Threonate can benefit a wide range of people, including:
- Students and professionals who need sharper focus and memory retention
- Adults over 40 looking to support long-term brain health
- People experiencing high stress, brain fog, or poor sleep
- Biohackers and wellness enthusiasts seeking cognitive enhancement
In short: if you have a brain, you might want to feed it this form of magnesium.
Signs You Might Need It
Magnesium deficiency is surprisingly common, especially if you’re dealing with:
- Brain fog or forgetfulness
- Trouble focusing
- Anxiety or stress overload
- Poor sleep quality
- Muscle twitching or tightness
While traditional magnesium supplements can support general wellness, Magnesium L-Threonate is the only form clinically proven to increase magnesium levels in the brain — making it a true game changer for cognitive health.
How to Take Magnesium L-Threonate
For optimal results, the recommended dosage is 3 capsules per day, taken in divided doses:
- Take 1 capsule in the morning to support daytime focus and mental clarity
- Take 2 capsules about two hours before bed to promote relaxation, cognitive recovery, and quality sleep
By splitting the schedule, you'll align with your body’s natural rhythm. This will help you stay sharp during the day and restful at night. As always, it's important to be consistent to see results.
NOW Foods is a reputable brand available from +boost because it uses the Magtein® patented form backed by clinical studies.
Are There Any Side Effects?
Magnesium L-Threonate is generally well tolerated, especially compared to other magnesium types that can cause digestive issues. In rare cases, some may experience:
- Mild drowsiness (especially when taken in high doses)
- Headaches (rare, often due to changes in neurotransmitter levels)
It’s always a good idea to talk to a healthcare provider if you're on medications or managing a neurological condition, but for most people, this supplement is very safe.
The Brain-Smart Takeaway
raise magnesium levels in the brain, and that makes a real difference when it comes to memory, focus, and overall brain health.
If you’re looking to stay mentally sharp, reduce brain fog, or support your cognitive health as you get older, this could be a great addition to your routine.
Ready to Try Magnesium L-Threonate?
+boost Malta currently stocks Magnesium L-Threonate from NOW® Foods, a trusted brand known for quality and clinical-grade formulas. It’s a great option if you want to start seeing the brain benefits of this unique form of magnesium.
In the meantime, don’t forget the basics: sleep well, stay hydrated, and stick with a supplement routine that supports how you want to feel each day.