If you’re on social media, you’ve undoubtedly seen the latest Beberine fad. Berberine is gaining popularity on social media sites such as TikTok for its weight loss properties, with some dubbing it “nature’s Ozempic.” In this blog, we’ll outline the science behind Berberine to help you answer the question: “Can Berberine help you lose weight?”
Why are people saying Berberine can help you lose weight?
Berberine is a natural bioactive chemical that can be found plants, including barberry, goldenseal, and Chinese goldthread. It has been utilized in traditional medicine systems for many years, particularly in Ayurvedic and Chinese medicine. Berberine supplements are used to help with blood sugar control, reduce insulin sensitivity, reduce inflammation, manage cholesterol, and lower appetite.
The science behind Berberine supplements
Hundreds of studies have been conducted on Berberine. According to animal research, one of the principal functions of Berberine is to activate an enzyme inside cells called AMP-activated protein kinase (AMPK). AMPK is located in cells throughout your body and regulates metabolism and energy levels.
Let’s dive into the health benefits of Berberine:
Lowers blood sugar
Berberine can reduce blood sugar levels in a variety of ways. As we said above, it activates the AMPK enzyme, which aids in the regulation of glucose metabolism. In addition, Berberine boosts glucose absorption in cells and decreases sugar production.
Reduces insulin resistance
Insulin, produced by the pancreas, is essential for controlling blood sugar (glucose) levels. When you consume carbs, your body converts them into glucose, which enters your bloodstream. Insulin functions like a key, allowing glucose to enter and be used for energy. Individuals with insulin resistance struggle to transport glucose into the cells, causing blood sugar levels to rise and an increased risk of Type 2 diabetes.
Berberine improves insulin sensitivity, allowing cells to respond to insulin more effectively. It accomplishes this by boosting insulin receptor expression and activation on cell surfaces.
Metabolism and weight management
Berberine may help with weight loss and metabolic health. It has an impact on several metabolic processes. For example, Berberine stimulates AMPK, which aids in regulating energy balance and fat metabolism. It also influences gene expression related to lipid metabolism, resulting in less fat accumulation and more fat burning. Berberine can also lower hunger and reduce dietary fat absorption, which aids in weight loss efforts.
Anti-inflammatory and antioxidant effects
Berberine has anti-inflammatory and antioxidant effects that can assist the body minimise chronic inflammation and oxidative stress. Berberine may help to prevent or treat inflammatory diseases by blocking inflammatory pathways and lowering the generation of pro-inflammatory chemicals.
How does Berberine differ to Ozempic?
While both Berberine and Ozempic have some weight-loss effects, they do so via different methods. Ozempic mirrors the activity of GLP-1, which helps reduce food intake and appetite by increasing insulin production, decreasing glucagon secretion, and slowing gastric emptying. On the other hand, Berberine’s weight reduction effects are likely to be mediated by various pathways, including AMPK activation and increases in insulin sensitivity.
Is Berberine safe?
Berberine must be consumed by adults only. It is important to note that this product should not be used if you are pregnant, may become pregnant, or are breastfeeding. While Berberine generally has an outstanding safety profile, it may cause mild gastrointestinal discomfort. If you are taking medications, especially for diabetes, or if you have a medical condition, it is crucial to consult your physician before using this product. The recommended dosage is 400 mg three times per day before meals.
Although the main side effects of Berberine are related to digestion, such as diarrhea, constipation, and bloating, these occurrences are typically rare.
The bottom line
In conclusion, because of its growing popularity, many refer to Berberine as “Nature’s Ozempic.” This comparison is based on the similarities in weight reduction effects of Berberine and the pharmaceutical medicine Ozempic. Berberine’s health advantages have been thoroughly researched, including its effect on blood sugar regulation, insulin sensitivity, and metabolism. Its capacity to activate AMPK, regulate glucose metabolism, and aid in weight management has prompted comparisons to Ozempic’s actions. However, while Ozempic is a regulated prescription drug that is prescribed for particular medical conditions, Berberine is available as a natural dietary supplement.